Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

Purpose:

AbbVies CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through preclinical development. You will work at the intersection of synthetic biology and immune modulation. The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs.

Key Responsibilities:

• Design and execute in vitro assays to evaluate CAR-T biology, including assessment of cytotoxicity, T-cell effector function, and immune cell phenotyping.

• Independently establish, track, and deliver on project milestones and experimental timelines, ensuring alignment with program objectives and organizational priorities, while adapting to evolving scientific needs.

• Organize, analyze, and synthesize complex scientific data, and effectively communicate experimental strategies, results, and interpretations to internal and external stakeholders through clear and impactful presentations and scientific reports.

• Maintain comprehensive and well-documented records in an Electronic Lab Notebook (ELN).

Qualifications

• BS, or equivalent education, with typically 7 or more years of experience; or MS, or equivalent education, with typically 5 or more years of experience, in immunology, cell and molecular biology, or related field.

• Demonstrated ability to independently design, perform, and interpret key experiments to address scientific questions. Proven capacity to quickly learn and apply new laboratory techniques. Able to manage multiple tasks efficiently while meeting deadlines. Strong skills in scientific writing and verbal communication.

• Previous experience in chimeric antigen receptor (CAR) construct design, CAR-T production, and T cell function evaluation.

• Deep expertise in primary T cell isolation, activation, transduction, T cell cytotoxicity, proliferation, cytokine profiling, multi-color flow cytometry, and immunological assays (e.g., ELISA, Luminex, cytotoxicity assays) is required.

• Experience in cell-basedin vitroassay development and semi-automated liquid handling systems for high-throughput workflows is a plus.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this roleat thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on manyfactors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible toparticipate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount isearned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat areallocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Companys sole and absolutediscretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html