Project Chemist (Mass Spectrometry)
- Employer
- Eagle Analytical
- Location
- Houston, Texas
- Posted date
- Aug 22, 2026
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- Discipline
- Science/R&D, Chemistry
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Lone Star Bio
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Job Details
Job Details Description
What We Are Looking For
We are seeking a motivated Project Chemist to support routine LC-MS–based analysis in a fast-paced laboratory environment. This role is responsible for the timely and reliable execution of LC-MS/MS workflows, including sample preparation, instrument operation, troubleshooting, and data review. The ideal candidate is comfortable working with minimal supervision, maintaining instrument performance, and delivering high-quality analytical results in a timely manner.
What You Will Do
Perform routine LC-MS based assays including peptide mapping, intact mass analysis and protein/small molecule quantitation in a timely and compliant manner
Prepare samples, standards, mobile phases, buffers, and other laboratory solutions
Operate and maintain LC-MS/MS and HPLC/UHPLC systems following SOPs
Conduct routine analytical runs and monitor instrument performance
Review, organize, interpret, and document analytical data and laboratory records
Identify and report unexpected test results, providing initial troubleshooting where applicable.
Perform system suitability, calibration, and QC checks
Troubleshoot basic instrument and method issues
Maintain laboratory cleanliness, inventory, and organization
Support method optimization and validation activities as appropriate
Collaborate with cross-functional team members to support project timelines and deliverables
Who You Are
Bachelor’s or Master’s degree in chemistry, Analytical Chemistry, Biochemistry, or related field
Hands-on experience with LC-MS/MS instrumentation and workflows
Experience with mass spectrometry–based protein and peptide characterization, including sample preparation, instrument operation, and data analysis, preferred
Experience with LC-MS/MS quantitation using MRM and/or SIR acquisition modes preferred
Hands-on experience with HPLC or UHPLC systems
Familiarity with biological and/or chemical sample matrices
Experience with basic wet chemistry and sample preparation techniques
Familiarity with GMP (Good Manufacturing Practices) and applicable regulatory requirements (e.g., FDA, ICH)
Strong attention to detail, organizational skills, and documentation practices
Comfortable working with laboratory software and data management systems
Ability to work independently as well as collaboratively in a team environment
Strong verbal and written communication skills
Preferred Experience
Hands-on experience with HPLC, UPLC, and MS instrumentation.
Knowledge of peptide synthesis and purification techniques.
Experience in a pharmaceutical or biotechnology setting.
Understanding of protein chemistry and post-translational modifications.
Who We Are
Serving customers since 2004, Eagle offers the highest quality in preparation testing for sterility, bacterial endotoxins, microbial detection, beyond-use dating (BUD) determination and active ingredient potency. State-of-the-art equipment, combined with the experience and knowledge of our team, makes Eagle the best choice for all testing needs. The Eagle team is committed not only to performing the best quality control testing but also working relentlessly with our customers on solutions if tests receive unexpected results. Learn more at www.eagleanalytical.com.
Qualifications Skills Preferred
Analytical Instrumentation Advanced
Behaviors Preferred
Dedicated: Devoted to a task or purpose with loyalty or integrity
Innovative: Consistently introduces new ideas and demonstrates original thinking
Team Player: Works well as a member of a group
Detail Oriented: Capable of carrying out a given task with all details necessary to get the task done well
: Motivations Preferred
Self-Starter: Inspired to perform without outside help
Job Security: Inspired to perform well by the knowledge that your job is safe
Goal Completion: Inspired to perform well by the completion of tasks
Growth Opportunities: Inspired to perform well by the chance to take on more responsibility
: Education Preferred
Bachelors or better in Analytical Chemistry or related field.
Bachelors or better in Biochemistry or related field.
Bachelors or better in Chemistry or related field.
Masters or better in Analytical Chemistry or related field.
Masters or better in Biochemistry or related field.
Masters or better in Chemistry or related field.
Experience
Licenses & Certifications Preferred
Certification in HPLC
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
Company
Eagle, established in 2003, began as a dedicated partner addressing regulatory needs in the compounding industry. Over the years, it has evolved into a premier scientific solutions provider, with a distinguished FDA-registered CGMP testing/calibration laboratory spanning over 80,000 square feet. Equipped with state-of-the-art instrumentation, cutting-edge technologies, and advanced methodologies, Eagle delivers tailored, high-quality scientific solutions designed to meet the most rigorous industry standards.
Eagle is uniquely positioned to serve a diverse range of clients, including pharmaceutical drug and device manufacturers, 503B outsourcing facilities, 503A compounding pharmacies, hospitals, and clinical research organizations. We proudly serve clients throughout North America and globally.
Eagle’s Mission
Our desire, dedication, and discipline to ensure that patient safety is at the forefront of everything we do and our holistic approach to resolving your compliance needs make Eagle a truly unique organization.
Our Vision
To guide and educate pharmacists and healthcare professionals to utilize fact-based decision-making to create science-based solutions. Research and develop innovative scientific approaches to solve healthcare challenges.