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Principal Research Scientist I, Depression Discovery

Employer
Missing Recruiter 397714
Location
Cambridge, MA
Posted date
Aug 25, 2026
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Discipline
Regulatory, Science/R&D, Biotechnology, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Genetown

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Job Details


Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.


Job Description

We are seeking an experienced and highly motivated scientist to join our Pharmacology and Cell Biology group within Discovery Psychiatry.The incumbentwillbe expected tooversee ongoing work in the grouprelated to depression cell-based models, plan for future capabilities expansion, andmay lead current or future drug discovery efforts.The ideal candidate will haveexperience with supervising scientific work,delivering high quality resultsand developing scientists.The position requires strongdrug discovery experienceand proven track record ofleading multidisciplinary teams toprogress projectsthroughpreclinical development. This is an excellent opportunity to work at the forefront of psychiatric research as part of a dynamic and growing team.
Key Responsibilities:

  • Develop strategy and overseeimplementationof internal modelsbeing used for depressiondrug development, especially in vitro iPSC-based models

  • Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas

  • Supervise junior scientists,providing scientific and technical leadership in the design and execution of experiments, and be accountable for the effectivedevelopment andperformance of the team

  • Serve as biologyleadfor current or future drug discovery projects,responsible forcoordinatingcross-functionalactivitiesandrepresenting teamat governance forumsfromHitGeneration throughCandidateNomination

  • Provide input onthe identification and selection of new targets, especially those related to depression

  • Collaborate with colleagues at various AbbVie and external sites

  • Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents

  • Ensure consistency and quality of technical reports


Qualifications

Qualifications:

  • MSor PhD inNeuroscience,Biological Sciences, Pharmacology,or related discipline with typically14+ (BS),12+ (MS), or 6+ (PhD) years of experienceinindustry and/or academia

  • Strong background inpsychiatryresearch and drug development,especially depression

  • Proven track record inprogressing projects through preclinicaldiscovery and into early development

  • Experience inworking in multidisciplinary teamsto accomplish strategic goals

  • Experience managing direct reports,includingproviding performance evaluations and development opportunities

  • Excellent organizational skills and the ability to manage multiple projects simultaneously

  • Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment

  • Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strongcan-doattitude

Preferred Qualifications:

  • Experience in psychedelics researchand drug discovery

  • Experience inoverseeingand pioneering the use of novelin vitroiPSC-basedmodelsfor psychiatry research


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

  • The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

  • This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

By clicking apply, your email address will be shared with the employer.